Publications by authors named "D V Messadi"

Article Synopsis
  • Head and neck squamous cell carcinoma (HNSCC) is a common and aggressive cancer with low survival rates, emphasizing the need for new treatment targets.
  • * Integrin αV (ITGAV) is found to be upregulated in HNSCC, with higher levels linked to poorer survival outcomes and greater invasiveness in specific cancer cell lines.
  • * The study highlights that ITGAV plays a key role in the spread of HNSCC cells, and its expression may be controlled by the SOX11 protein.
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Background: Tongue squamous cell carcinoma (TSCC) represents one of the major subsets of head and neck cancer, which is characterized by unfavorable prognosis, frequent lymph node metastasis, and high mortality rate. The molecular events regulating tongue tumorigenesis remain elusive. In this study, we aimed to identify and evaluate immune-related long non-coding RNAs (lncRNAs) as prognostic biomarkers in TSCC.

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Late detection and specialist referral result in poor oral cancer outcomes globally. High-risk LRMU populations usually do not have access to oral medicine specialists, a specialty of dentistry, whose expertise includes the identification, treatment, and management of oral cancers. To overcome this access barrier, there is an urgent need for novel, low-cost tele-health approaches to expand specialist access to low-resource, remote and underserved individuals.

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The development of head and neck squamous cell carcinoma (HNSCC) is a complex pathological process and many cellular and molecular events may occur. The ubiquitin conjugating enzyme E2 (UBE2C) was found to play an oncogenic role in several human cancers. However, its functional role in HNSCC tumorigenesis remains unknown.

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