[Photochemiluminescent study of the antioxidant activity in biological systems. Mathematical modeling].

The mathematical modeling of the kinetics of riboflavin photo-chemiluminescence (PCL) in the presence of antioxidants, superoxide dismutase and ascorbic acid, has been performed. A specially developed computer program "Kinetic Analyzer" was used for the modeling. The PCL intensity of was taken as directly proportional to the superoxide concentration, because lucigenin had been added to the system.

[A simple method of measuring superoxide dismutase activity using photochemiluminescence].

At present, photochemical detection of SOD-activity is used in most cases, where superoxide production is based on the NADPH oxidase activity or autooxidation of some substances, for instance, adrenaline. The shortcomings of these assays are the requirement of stable pH and temperature and need long-term experiments and sophisticated preliminary work. For this reason a novel method to determine SOD activity have been proposed, based on the photochemiluminescence (PCL), where riboflavine is used as a photosensitizer and lucigenin as a free-radical detector.

The maintenance of curriculum-development activities in government medical schools in Indonesia.

This paper reports information obtained from 499 participants during the course of a national series of workshops conducted in eleven government medical schools in Indonesia. The information analysed provided an independent check of claims made by previous investigators relating to the extent to which Indonesian medical schools had progressed towards curriculum re-organization consistent with national policy for the reform of undergraduate medical training. The majority of participants had developed and completed course programmes based on instructional objectives, which was seen as being broadly consistent with previous claims.

Gas chromatography of sample monocarbonyls in cigarette whole smoke as the benzyloxyamine derivatives.

A qualitative and semi-quantitative method was established for the investigation of low-molecular-weight volatile carbonyl compounds in cigarette whole smoke. The carbonyls were trapped on a silica gel "column" and eluted with water. The aqueous solution was then treated with benzyloxyamine to form the corresponding oximes, which were then separated on a short (12 m) FFAP glass-capillary gas chromatographic column with temperature programming, and detected by a nitrogen selective detector.

Simultaneous quantitative GLC determination of chlorpheniramine maleate and phenylpropanolamine hydrochloride in a cold tablet preparation.

A GLC method was developed for the simultaneous determinations of chlorpheniramine maleate and phenylpropanolamine hydrocholride in a cold tablet preparation containing a large amount of aspirin. The method utilizes a solid sampling device to eliminate interference from solvent, and it is rapid and precise. The total analysis time is less than 1.