Evaluation of Microcirculation, Cytokine Profile, and Local Antioxidant Protection Indices in Periodontal Health, and Stage II, Stage III Periodontitis.

Periodontitis, initiated by the subgingival biofilm and modified by the individual's inflammatory/immune response, has been associated with vascular dysfunction. To analyze microcirculation indices in periodontal tissues and determine the activity of the enzymatic component of antioxidant defense and humoral immunity factors, a single-blind non-invasive clinical trial was realized. Forty subjects, aged from 30 to 65 years, with moderate to severe chronic periodontitis (chronic generalized periodontitis, CGP) vs.

[Experimental substantiation of recombinant epidermal growth factor use efficacy in the treatment of wounds of mucosal membrane of oral cavity in the immunodeficiency].

In experiment on rats in the immunodeficiency the use of recombinant epidermal growth factor was substantiated that let to speed up reparative regeneration at concentration 500 ppb/l drinking water.