Publications by authors named "D V Griffiths"

Background: Dose administration aids (DAA) are widely used to improve adherence. In New Zealand (NZ) more pharmacies are utilizing automated filling robots to meet DAA demand. Pradaxa™ capsules containing dabigatran etexilate (DE) is problematic.

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The Haloferacaceae are a family of extremely halophilic archaea with many species producing enzymes and products beneficial for industrial biotechnology. They are, however, relatively under-characterised with regards to genetics and gene products. This study aims to use existing sequence data to highlight genetic diversity, create pangenomes for three genera, and provide secondary metabolite and pathway analysis.

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The 2022 mpox epidemic predominantly affected gay, bisexual, and other men who have sex with men (GBM). Led by a provincial community program and co-galvanized by clinician-researchers, GBM community leaders in Ontario coordinated a robust response, representing a reproducible strategy for community engagement and mobilization during future epidemics.

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Article Synopsis
  • * A case was presented involving a 21-year-old woman with several health issues, including bilateral glaucoma and radiculomegaly, confirmed through cone-beam CT scans.
  • * Genetic testing identified a specific mutation related to OFCD syndrome, and further scans revealed an atrial septal defect that was surgically repaired, highlighting the critical role of diagnosing radiculomegaly for effective clinical management and cardiac evaluations.
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Article Synopsis
  • Colonic atresia (CA) is often found alongside Hirschsprung disease (HD) in about 10% of cases, leading some surgeons to opt for a diversion during initial surgery.
  • In a study using data from the Pediatric Health Information System, it was found that 9.5% of CA patients were diagnosed with HD, with a significant portion undergoing initial diversion.
  • Patients who had primary anastomoses experienced fewer operations and needed more parenteral nutrition, but overall outcomes were similar, suggesting that performing primary anastomosis is a safe option in CA cases where intraoperative biopsies are taken.
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