Publications by authors named "D V Enikeev"

Article Synopsis
  • Hyperhomocysteinemia (hHCY) is linked to increased plasma homocysteine levels and correlates with a higher risk of migraines, especially those with aura.
  • The study investigated how hHCY affects cortical spreading depression (CSD) and neuronal activity in the somatosensory cortex of rats, highlighting an increased excitability and more frequent CSDs in those with hHCY.
  • Results showed impaired CSD propagation and delayed recovery of brain activity in hHCY animals, indicating that prolonged high homocysteine levels may increase the risk of migraine-associated brain injuries.
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In this paper, we explore the usage of decision aids, patient information leaflets (PILs), videos, social media and modern technology to empower patients and enable shared decision-making (SDM). It explores the role of enhanced consent processes in urology. A re-evaluation of the conventional consent process is required towards more patient-centred care and SDM, which prioritises patient education and understanding of their medical conditions and treatment pathways.

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Introduction: Metastatic castration-resistant prostate cancer (mCRPC) is the most severe form of prostate cancer, developing in about 30% of patients; standard approaches of its treatment often remain ineffective. The development of theranostics principle and the discovery of the prostate-specific membrane antigen (PSMA) make it possible to implement a new approach in the treatment of patients with mCRPC - PSMA-targeted therapy. It is based on the use of a specific radionuclide (alpha or beta-minus emitter) associated with a ligand (radioligand) that binds to PSMA and has a targeted effect on tumor cells.

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Purpose: Uric acid stones (UAS) can be treated non-invasively by oral chemolysis. However, it is crucial to identify individuals who are most likely to benefit from this approach, specifically, patients with pure UAS. The aim of this study was to develop a nomogram that can differentiate between pure and mixed UAS.

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Article Synopsis
  • The study looks at how the size of the prostate affects patients’ recovery and symptoms after a surgery called RASP, which helps treat an enlarged prostate (BPH).
  • They reviewed 25 articles and found that patients with smaller prostates had worse symptoms before surgery but improved more after, while those with larger prostates still had some moderate symptoms.
  • The researchers concluded that RASP is a safe and effective surgery for treating BPH, but more studies are needed to understand how prostate size influences the results.
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