Publications by authors named "D V Chavda"

Article Synopsis
  • * It outlines the authors' experience with a transcranial endovascular approach as a solution for these difficult cases.
  • * The findings suggest that this method is both safe and effective for treating dAVF when other access routes aren't viable.
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Intrinsically disordered proteins (IDPs) are a novel class of proteins that have established a significant importance and attention within a very short period of time. These proteins are essentially characterized by their inherent structural disorder, encoded mainly by their amino acid sequences. The profound abundance of IDPs and intrinsically disordered regions (IDRs) in the biological world delineates their deep-rooted functionality.

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Article Synopsis
  • A review was conducted on the impact of the ketogenic diet on epilepsy treatment in children and adolescents, following systematic guidelines and including 12 qualifying studies.
  • The ketogenic diet showed positive results in reducing the frequency and severity of seizures while presenting manageable side effects like gastrointestinal issues and dehydration.
  • Variations of the ketogenic diet were found beneficial for seizure management, serving as either a complementary or alternative treatment for young patients with epilepsy.
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Objective: The primary limitations of tadalafil in treating erectile dysfunction are its low solubility and unpleasant bitter taste, which ultimately result in inadequate patient adherence. The present study aimed to develop and characterize a medicated chocolate formulation containing Tadalafil and β-CD (solubility enhancer) employing the concept of Design of Experiment (DoE) using chocolate as a user-friendly excipient.

Methods: An inclusion complex was formulated by incorporating the drug into β-CD using the kneading method for solubility improvement and also as a taste masker for Tadalafil.

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Carrageenans are industrially important polysaccharides with tunable viscoelastic and gelation properties. The function of polysaccharide depends on its conformation and chemical composition. However, the solution conformations of carrageenans are highly debated, and the structure-function relationship remains elusive.

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