Publications by authors named "D V Agoston"
This review systematically analyzes potential biomarker candidates for post-traumatic epilepsy (PTE) in humans who have experienced moderate to severe traumatic brain injury (TBI). Focusing on biomarkers across biofluid-based protein, genetic, neuroimaging, and neurophysiological categories, this review distinguishes between TBI patients who develop PTE and those who do not. The review adheres to established methodologies outlined in the Cochrane Handbook for Systematic Reviews of Interventions.
View Article and Find Full Text PDFThe purpose of this study was to assess the performance of predictive blood biomarkers for responsiveness to targeted treatments for chronic psychological issues years after traumatic brain injury (TBI). Targeted Evaluation Action and Monitoring of TBI was a prospective 6-month interventional trial of participants with chronic TBI sequelae ( = 95). Plasma biomarkers were analyzed pre-intervention: glial fibrillary acidic protein (GFAP), tau, hyperphosphorylated tau Thr231 (p-Tau), von Willebrand factor (vWF), brain lipid-binding protein (BLBP), ubiquitin C-terminal hydrolase-L1 (UCH-L1), vascular endothelial growth factor-a (VEGFa), and claudin-5 (CLDN5).
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- Electrochemotherapy (ECT) is gaining traction as an effective treatment for tumors in the head and neck, but there's limited data on its use for eyelid-periocular skin tumors, specifically basal cell carcinoma (BCC).
- This study reports on the long-term results of ECT treatments in 19 patients with eyelid-periocular BCC, adhering to European guidelines and using bleomycin as the primary drug.
- The study found a 100% overall response rate and a 95% complete response rate, with only 15.8% of patients experiencing recurrence during an average follow-up of 78.9 months, indicating ECT's effectiveness and safety for this type of cancer.
Major determinants of the biological background or reserve, such as age, biological sex, comorbidities (diabetes, hypertension, obesity, etc.), and medications (e.g.
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