Publications by authors named "D U Sinclair"

Background And Aim: Unmet need for social care is linked to numerous adverse health outcomes. Understanding which unmet needs have the biggest impact on healthy ageing could help resource-stretched services prioritise care. To address this evidence gap, our analysis aimed to explore the association between selected individual unmet care needs and an indicator of healthy ageing.

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Objective: To understand how area deprivation inequalities in COVID-19 mortality changed during the national vaccination programme in England and to identify the extent to which these inequalities might be explained by unequal vaccination uptake.

Design: Ecological study.

Setting: 307 Lower Tier Local Authorities in England, March 2020 - December 2022.

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Global disparities in neurosurgical care necessitate innovations addressing affordability and accuracy, particularly for critical procedures like ventriculostomy. This intervention, vital for managing life-threatening intracranial pressure increases, is associated with catheter misplacement rates exceeding 30% when using a freehand technique. Such misplacements hold severe consequences including haemorrhage, infection, prolonged hospital stays, and even morbidity and mortality.

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Introduction: Heart failure (HF) is a complex clinical syndrome. Accurate risk stratification and early diagnosis of HF are challenging as its signs and symptoms are non-specific. We propose to address this global challenge by developing the STRATIFYHF artificial intelligence-driven decision support system (DSS), which uses novel analytical methods in determining the risk, diagnosis and prognosis of HF.

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