Publications by authors named "D Trichopoulos"
Several studies have reported associations of hypertension with cancer, but not all results were conclusive. We examined the association of systolic (SBP) and diastolic (DBP) blood pressure with the development of incident cancer at all anatomical sites in the European Prospective Investigation into Cancer and Nutrition (EPIC). Hazard ratios (HRs) (95% confidence intervals) were estimated using multivariable Cox proportional hazards models, stratified by EPIC-participating center and age at recruitment, and adjusted for sex, education, smoking, body mass index, physical activity, diabetes and dietary (in women also reproductive) factors.
View Article and Find Full Text PDFPublished associations between dietary folate and bladder cancer risk are inconsistent. Biomarkers may provide more accurate measures of nutrient status. This nested case-control analysis within the European Prospective Investigation into Cancer and Nutrition (EPIC) investigated associations between pre-diagnostic serum folate, homocysteine, vitamins B6 and B12 and the risk of urothelial cell carcinomas of the bladder (UCC).
View Article and Find Full Text PDFThe epidemiological evidence regarding the association of coffee and tea consumption with prostate cancer risk is inconclusive, and few cohort studies have assessed these associations by disease stage and grade. We examined the associations of coffee (total, caffeinated and decaffeinated) and tea intake with prostate cancer risk in the European Prospective Investigation into Cancer and Nutrition. Among 142,196 men, 7,036 incident prostate cancer cases were diagnosed over 14 years of follow-up.
View Article and Find Full Text PDFBackground: No studies have estimated disability-adjusted life-years (DALYs) lost due to hip fractures using real-life follow-up cohort data. We aimed to quantify the burden of disease due to incident hip fracture using DALYs in prospective cohorts in the CHANCES consortium, and to calculate population attributable fractions based on DALYs for specific risk factors.
Methods: We used data from six cohorts of participants aged 50 years or older at recruitment to calculate DALYs.
Article Synopsis
- The study evaluates the link between self-rated health (SRH) and mortality among elderly individuals (60+) in Europe and the U.S., utilizing data from 424,791 participants over a median follow-up of 12.5 years.
- It finds that those rating their health as "fair" or "poor" have a significantly higher risk of death from all causes, particularly cardiovascular issues, with specific hazard ratios indicating increased mortality risk.
- Factors that positively influence SRH include being younger, having higher education levels, being married or cohabiting, staying physically active, and maintaining a healthy body weight; improving these factors may help older adults feel and be healthier.