[Unusual twin pregnancy: one in the pseudo-unicornate uterus and the other in the rudimentary uterine horn. Discussion on the diagnosis and management during pregnancy].

An unusual twin pregnancy was diagnosed echographically at 18 weeks gestation and confirmed by magnetic resonance imaging. One foetus was in a pseudo unicornis uterus and the other in a rudimentary uterus cornu. The risk in such cases, as also reported in the literature, is rupture of the rudimentary cornu at about 20 weeks gestation.

[Giant breast fibroadenoma].

We report a case of giant fibroadenoma of the breast, "juvenile type", in a 15 year old girl. We study the characteristics of this tumor that occurs in adolescents females, the differential diagnosis with cystosarcoma phylloide and benign virginal hypertrophy, and treatment. Follow-up is recommended because of possible recurrent tumor of a short time.

[Hematocolpometra and local estrogen therapy: an overdose of promestriene?].

We report a case of hyperestrogenisation which showed itself by the presence of a haematocolpometra in an elderly lady which could be attributed to prolonged and continuous treatment with Promestriene cream. Haematocolpometra is due to intra-uterine haemorrhage (itself due to hyperplastic endometrial polyps) with vaginal stenosis caused by vaginal atrophy that existed before local treatment was started. The Pomestriene is an estrogenic substance which works locally and does not seem to cause much in the way of general effects when used for short courses.