Publications by authors named "D To"

Background: The Canadian Chiropractic Association (CCA) initiated a quality improvement project to develop best practices aimed at enhancing the patient experience.

Objectives: (1) Identify and prioritise the key moments in the new patient experience that could be improved by providing chiropractors with focused support and resources; (2) explore views, barriers, and enablers to implementing these best practices; and (3) develop recommendations to facilitate the adoption of these practices.

Methods: We conducted a qualitative needs assessment using a human-centred design approach, focused on understanding the needs and experiences of end-users to create tailored solutions.

View Article and Find Full Text PDF

Objective: Recent advances in large language models (LLM) offer opportunities to automate health coaching. With zero-shot learning ability, LLMs could revolutionize health coaching by providing better accessibility, scalability, and customization. The aim of this study is to compare the quality of responses to clients' sleep-related questions provided by health coaches and an LLM.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to assess how reverse micelles (RM) and hydrophobic ion pairs (HIP) can be used to incorporate semaglutide into self-emulsifying oral drug delivery systems.
  • Researchers created RM using a cationic surfactant (ELA) and anionic surfactant (DOC) and explored various lipophilic phases to determine solubility and dissolution rates of semaglutide.
  • The findings demonstrated that RM enhanced the lipophilicity and payload of semaglutide in SEDDS, with promising cytocompatibility and doubled permeability when tested on Caco-2 cells compared to HIP formulations.
View Article and Find Full Text PDF

For the design of charge-converting nanocarriers (NCs), cationic lipid-based NCs containing curcumin as model drug were coated with phosphorylated starch (NC-SP) and phosphorylated dextran (NC-DP). NCs showed a drug encapsulation efficiency of 94 % and had a mean size of 175 to 180 nm. The recorded zeta potential of the core NC (cNC) was +8.

View Article and Find Full Text PDF