Publications by authors named "D Thein"

Background: The epidemiology of chronic hand eczema (CHE) remains poorly examined.

Objective: To investigate the prevalence of CHE in a general adult population and describe the characteristics of affected individuals.

Methods: We investigated the prevalence and characteristics of CHE using a random sample from the general Danish population (The Danish Skin Cohort).

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Background: Hospitalizations are a major burden for both patients and society but are potentially preventable. We examined the one-year hospitalization burden in patients undergoing transcatheter aortic valve replacement (TAVR) and compared hospitalization rates and patterns with those undergoing isolated surgical aortic valve replacement (SAVR).

Methods: Using Danish nationwide registries, we identified patients who underwent first-time TAVR and isolated SAVR (2008-2019), respectively.

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Article Synopsis
  • - The study aimed to determine how a patient's treatment journey before starting biologic drugs affects the durability of those treatments for psoriasis, utilizing data from Danish national registries over a period from 2010 to 2021.
  • - 2496 patients were analyzed, with a majority on adalimumab, and results showed that about 78.2% discontinued treatment during an average follow-up of 5 years.
  • - Ultimately, the study concluded that the complexity of the pre-biologic treatment journey did not have a significant impact on the survival rate of biologic drugs in these patients.
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Importance: Alopecia areata (AA) carries a psychological burden for patients beyond hair loss. However, quality-of-life measurement tools such as EQ-5D used in clinical trials may not adequately capture the burden of AA, the perceived stigmatization or the psychosocial impact of AA.

Objective: To investigate the potential association between disease severity and the degree of social isolation, perceived stigmatization, anxiety and depression, alcohol consumption and work absenteeism using multiple PRO measures in patients with AA.

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