Publications by authors named "D Tanasescu"
Article Synopsis
- - Hashimoto's thyroiditis (HT) is a significant autoimmune thyroid disease where patients often present with asthenia (fatigue), presenting challenges in differentiating it from other conditions; this study aimed to analyze the relationship between HT and asthenia in newly diagnosed patients.
- - Conducted between July 2022 and July 2023 across multiple university hospitals, the study included 120 patients, divided into an asthenia group (49.2%) and a non-asthenia group, discovering that asthenia was linked to a higher incidence of headaches and hypothyroidism but thyroid function tests were similar between both groups.
- - The findings suggest that asthenia may not be a strong indicator of thyroid dysfunction
Background: Medullary thyroid carcinoma (MTC), the third most frequent histological type of thyroid malignancy, may be found isolated or as part of multiple endocrine neoplasia type 2 (MEN2). One particular subtype of this autosomal dominant-transmitted syndrome includes an association with cutaneous lichen amyloidosis, although, generally, a tide genotype-phenotype correlation is described in patients who carry proto-oncogene pathogenic variants.
Methods: Our objective was to provide an endocrine perspective of a case series diagnosed with -positive familial MTC associated with cutaneous primary lichen amyloidosis amid the confirmation of MEN2.
Asymptomatic primary hyperparathyroidism (PHPT) involves 80-90% of the parathyroid tumor-associated cases of PHPT in the modern medical era, while normocalcemic PHPT (NPHPT) has a prevalence of 0.1-11%. We aimed to analyze the bone status and mineral metabolism in NPHPT amid conservative or surgical management.
View Article and Find Full Text PDFBackground: Malignant tumors represent a significant pathology with a profound global impact on the medical system. The fight against cancer represents a significant challenge, with multidisciplinary teams identifying numerous areas requiring improvement to enhance the prognosis. Facilitating the patient's journey from diagnosis to treatment represents one such area of concern.
View Article and Find Full Text PDFBreast cancer is one of the most common forms of neoplasia worldwide. The purpose of our observational study was to evaluate the status of HER2 overexpression among new cases of breast neoplasia with an impact on the natural history of breast cancer disease and therapeutic personalization according to staging. This study included 45 breast cancer patients which have an overexpression of HER2 through the mutation of the EGFR-ERBB2 receptor.
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