This observational study aimed to evaluate serum and urinary amino acid (AA) concentrations in healthy dogs and dogs with chronic kidney disease (CKD) fed a commercial therapeutic renal diet with reduced protein and phosphorus levels. Ten dogs with CKD stages 3 or 4 composed the study group and received the renal diet for 180 days (RG T180). A control group (CG T30) composed of seven healthy dogs was fed a renal diet for 30 days.
View Article and Find Full Text PDFChronic kidney disease (CKD) is highly prevalent in dogs, and metabolomics investigation has been recently introduced for a better understanding of the role of diet in CKD. This study aimed to compare the serum metabolomic profile of healthy dogs (CG) and dogs with CKD (CKD-T0 and CKD-T6) to evaluate whether the diet would affect metabolites. Six dogs (5 females; 1 male; 7.
View Article and Find Full Text PDFPure rotational spectra of ScC (X̃A) and ScCC (X̃A') have been measured using Fourier transform microwave/millimeter-wave methods. These molecules were synthesized in a DC discharge from the reaction of scandium vapor, produced via laser ablation, with CH or CH/CH, diluted in argon. The N = 1 → 0 2 → 1 3 → 2, and 4 → 3 transitions in the frequency range of 14 GHz-61 GHz were observed for both species, each exhibiting hyperfine splittings due to the nuclear spins of C (I = 1/2) and/or Sc (I = 7/2).
View Article and Find Full Text PDFToxins (Basel)
December 2019
An integrated study on the effect of renal diet on mineral metabolism, fibroblast growth factor 23 (FGF-23), total antioxidant capacity, and inflammatory markers has not been performed previously. In this study, we evaluated the effects of renal diet on mineral metabolism, oxidative stress and inflammation in dogs with stage 3 or 4 of chronic kidney disease (CKD). Body condition score (BCS), muscle condition score (MCS), serum biochemical profile, ionized calcium (i-Ca), total calcium (t-Ca), phosphorus (P), urea, creatinine, parathyroid hormone (PTH), FGF-23, interleukin 6 (IL-6), interleukin 10 (IL-10), tumor necrosis factor alpha (TNF-α) and total antioxidant capacity (TAC) were measured at baseline (T0) and after 6 months of dietary treatment (T6).
View Article and Find Full Text PDFPhys Chem Chem Phys
April 2018
The pure rotational spectrum of the AlC2 radical (X[combining tilde]2A1) has been measured using Fourier transform microwave/millimeter-wave (FTMmmW) techniques in the frequency range 21-65 GHz. This study is the first high-resolution spectroscopic investigation of this molecule. AlC2 was created in a supersonic jet from the reaction of aluminum, generated by laser ablation, with a mixture of CH4 or HCCH, diluted in argon, in the presence of a DC discharge.
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