Avian photopic curves show energy peaks at different wavelengths than humans, particularly in the ultraviolet, yellow, and red range. Therefore, an illumination system with a spectrum tailored for laying hens, encompassing the entire visible spectrum, can enhance performance and welfare. The primary contribution of this study was the development of two Spectral Power Distributions (SPDs) specifically designed for laying hens, with different spectral proportions (S1 and S2), and the evaluation of their effects on productive performance, egg quality, and hormonal levels, compared to conventional white lighting at 3000 K (C).
View Article and Find Full Text PDFOligodendrocyte progenitor cells differentiate into oligodendrocytes, which myelinate axons during development and following demyelinating injury. However, the mechanisms that drive the timing and specificity of developmental myelination are not well understood. We hypothesized that oligodendrocyte progenitor cell proliferation and differentiation would be affected by pathological neuronal activity during adolescent development when developmental myelination is occurring and that this would also impact neuron-to-oligodendrocyte progenitor cell connectivity and myelination.
View Article and Find Full Text PDFObjective: To map nursing interventions that contribute to preventing posttraumatic stress in people hospitalized in the context of intensive care.
Design: Scoping review according to the Joanne Briggs Institute methodology.
Methods: The search was carried out in the databases PubMed, CINAHL via EBSCO, Joanna Briggs Institute Database of Systematic Reviews, COCHRANE Database of Systematic Reviews, Repositório Científico de Acesso Aberto de Portugal, Dans Easy, and Dart-Europe.
Background: Herein, we present the results of the phase 2 IMMUNOSARC study (NCT03277924), investigating sunitinib and nivolumab in adult patients with advanced bone sarcomas (BS).
Methods: Progressing patients with a diagnosis of BS were eligible. Treatment was comprised of sunitinib (37.