Publications by authors named "D T Dempsey"
Traumatic brain injury (TBI) has been discussed as a risk factor for Alzheimer's disease (AD) due to its association with AD risk and earlier cognitive symptom onset. However, the mechanisms behind this relationship are unclear. Some studies have suggested TBI may increase pathological protein deposition in an AD-like pattern; others have failed to find such associations.
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- Limited research has examined how cardiovascular risk and amyloid levels influence cognitive decline in East Asians, specifically in a study involving 526 participants from the Korean Brain Aging Study.
- Results showed that cognitively normal individuals without amyloid (Aβ-) but with high cardiovascular risk scores had significantly lower cognitive performance than their low-risk counterparts.
- Ultimately, while managing vascular risk is important for early cognitive preservation in Aβ- individuals, amyloid pathology was found to be the main factor driving cognitive decline in both cognitively normal and mild cognitive impairment groups, regardless of vascular risk status.
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- The article outlines recent updates to virus taxonomy approved by the International Committee on Taxonomy of Viruses (ICTV) in April 2024.
- The ICTV invited members to vote on 203 taxonomic proposals, resulting in significant additions across various levels, including one new phylum and 3,547 new species.
- The total number of established virus species now stands at 14,690, following the ratification of proposals for species name formatting to the binomial system.
Atopic dermatitis (AD) is an inflammatory skin condition with a childhood prevalence of up to 25%. Microbial dysbiosis is characteristic of AD, with Staphylococcus aureus the most frequent pathogen associated with disease flares and increasingly implicated in disease pathogenesis. Therapeutics to mitigate the effects of S.
View Article and Find Full Text PDFThe BrainAGE method is used to estimate biological brain age using structural neuroimaging. However, the stability of the model across different scan parameters and races/ethnicities has not been thoroughly investigated. Estimated brain age was compared within- and across- MRI field strength and across voxel sizes.
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