Publications by authors named "D Suren"
Background: Primary ovarian mucinous tumors are uncommon. Factors leading to invasive progression and metastatic disease have not been fully delineated yet. The aim of this study is to determine the rates of p53 and p16 immunoexpressions in primary ovarian mucinous tumors, to investigate their relationship with clinicopathologic factors and their impact on prognosis and survival.
View Article and Find Full Text PDFPurpose: The primary aim of this study was to determine the prevalence of HPV in pterygium with polymerase chain reaction (PCR) testing and to investigate the relationship with clinicopathological factors. A secondary aim was to evaluate the relationship between HPV and the recurrence of pterygium.
Methods: The study included 60 patients.
Purpose: Vagal nerve stimulation (VNS) is an effective treatment for patients with epilepsy, depression, and other neuropsychiatric conditions. Understanding the tissue changes associated with VNS devices is crucial for optimizing patient outcomes and device development. This study aimed to investigate the histopathological changes in the tissues surrounding the VNS generator and explore potential correlations with clinical factors and battery performance.
View Article and Find Full Text PDFContext: HER2-targeted therapy has been shown to benefit HER2-positive gastric cancer. It is very important to determine the HER2 expression level correctly to select the appropriate test and sampling method.
Aim: In this study, we investigated the frequency of overexpression of HER2 and intratumoral heterogeneity of HER2-positive cases, comparison of HER2 used immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) performance in biopsy and resection specimens, the correlation of HER2 status between biopsy and resection specimens, and its relationship with clinicopathological findings.
Article Synopsis
- The study investigated the expression of the p16 tumor suppressor gene in pterygium and its association with epithelial dysplasia and HPV.
- Out of 75 pterygium cases, 65% showed low-grade dysplasia, and a significant portion tested positive for p16, with a much higher expression in pterygium than in the control group.
- The findings suggest that p16 expression in pterygium could indicate a link to HPV, highlighting the importance of further research into HPV's role in the development of the condition.