Spatial Ecology of a Resident Avian Predator During the Non-Breeding Period in Managed Habitats of Southeastern Europe.

Describing home range and resource selection is crucial for understanding ecological needs and creating conservation programs. Still, our knowledge of spatial and behavioural ecology for most species remains limited. Here, we used satellite transmitters to investigate core and home range sizes, habitat selection, and roost characteristics in seven tawny owl males in Western Serbia during the autumn-winter period 2023.

Doxycycline Trap: A Case Report on the Unexpected Development of an Oesophageal Ulcer.

The phenomenon of drug-induced mucosal damage has not been reported much in the literature, although over 100 drugs are known to cause this condition. Tetracyclines contribute the most to mucosal damage. The common symptoms are difficulty swallowing, pain while swallowing, and possibly retrosternal pain.

Comparison of ANN and XGBoost surrogate models trained on small numbers of building energy simulations.

Surrogate optimisation holds a big promise for building energy optimisation studies due to its goal to replace the use of lengthy building energy simulations within an optimisation step with expendable local surrogate models that can quickly predict simulation results. To be useful for such purpose, it should be possible to quickly train precise surrogate models from a small number of simulation results (10-100) obtained from appropriately sampled points in the desired part of the design space. Two sampling methods and two machine learning models are compared here.

Trehalose Attenuates In Vitro Neurotoxicity of 6-Hydroxydopamine by Reducing Oxidative Stress and Activation of MAPK/AMPK Signaling Pathways.

The effects of trehalose, an autophagy-inducing disaccharide with neuroprotective properties, on the neurotoxicity of parkinsonian mimetics 6-hydroxydopamine (6-OHDA) and 1-methyl-4-phenylpiridinium (MPP) are poorly understood. In our study, trehalose suppressed 6-OHDA-induced caspase-3/PARP1 cleavage (detected by immunoblotting), apoptotic DNA fragmentation/phosphatidylserine externalization, oxidative stress, mitochondrial depolarization (flow cytometry), and mitochondrial damage (electron microscopy) in SH-SY5Y neuroblastoma cells. The protection was not mediated by autophagy, autophagic receptor p62, or antioxidant enzymes superoxide dismutase and catalase.