Publications by authors named "D Spadaccini"
Background: Reducing obesity and weight gain, which often occurs during breast cancer treatment, may represent an efficient secondary or tertiary prevention against cancer.
Purpose: This retrospective observational cohort study aimed to assess the impact of a Mediterranean diet on weight and anthropometric changes in women completing active breast cancer treatment. Additionally, we sought to identify factors associated with study dropout within one year.
Effect of Soy Protein Supplementation on Muscle Adaptations, Metabolic and Antioxidant Status, Hormonal Response, and Exercise Performance of Active Individuals and Athletes: A Systematic Review of Randomised Controlled Trials.
Sports Med
December 2023
Article Synopsis
- Protein supplements, especially soy protein (SP), are essential for athletes and active individuals to support muscle repair and overall performance.
- This review examines clinical trials to compare the effects of SP with whey protein on muscle adaptations, metabolic health, hormonal responses, and exercise performance in young adults.
- Findings indicate that SP can enhance lean muscle mass and reduce some negative metabolic markers, while also showing improved antioxidant capacity compared to whey protein in long-term studies.
Background: Obesity treatment strategies mainly include outpatient lifestyle modification, drugs and bariatric surgery. Voluntary rehabilitative inpatient programs are gaining relevance as potential alternative settings of care that focus on weight loss and prevention of weight regain through a multidisciplinary approach, but their prevalence is still limited due to the high costs.
Aim: Considering the lack of evidence in this area, the objective of this study is to systematically review the currently available literature on non-pharmacological and non-surgical inpatient programs aimed at weight loss, to clarify the efficacy and the characteristics of these interventions.
Calreticulin and PDIA3, two markers of endoplasmic reticulum stress, are associated with metabolic alterations and insulin resistance in pediatric obesity: A pilot study.
Front Endocrinol (Lausanne)
October 2022
Article Synopsis
- The study assessed markers of endoplasmic reticulum (ER) stress in 52 children and adolescents, comparing those with obesity to normal weight controls.
- PDIA3 levels were significantly higher in obese children, showing positive relationships with Tanner stages and indicators of metabolic syndrome like insulin resistance and elevated cholesterol.
- Findings suggest that CALR and PDIA3 could serve as early indicators of metabolic issues related to obesity, potentially helping identify at-risk pediatric patients for future complications.
Background: Chronic kidney disease (CKD) is a global health issue. Evidence of the effectiveness of nutritional intervention on slowing time to dialysis is limited in Arab countries. Therefore, this study aims to contribute to current research by providing new insights on the efficacy of personalized nutritional intervention in pre-dialysis patients in the Kingdom of Bahrain.
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