Publications by authors named "D Soliman"
Objective: To compare in vitro fertilization treatment outcomes for the oral gonadotropin-releasing hormone (GnRH) antagonist elagolix (E) to the conventionally used injectable GnRH antagonist ganirelix (G) for achieving pituitary gonadotropin suppression during a controlled ovarian stimulation (COS) cycle.
Design: Retrospective cohort study.
Setting: Private university-affiliated fertility center.
Article Synopsis
- This study presents the first extensive report on Primary Myelofibrosis (PMF) in Qatar, covering data collected over 13 years, as there is a significant lack of information about PMF in the MENA region.
- Findings show that pre-PMF patients differ from overt PMF patients in terms of blood counts and genetic features, with overt PMF having a higher risk category and worse disease progression.
- The research provides important insights into the importance of the DIPSS plus scoring system, highlighting its effectiveness in identifying high-risk patients who face worse outcomes and increased treatment needs.
Article Synopsis
- Flagella are crucial for the movement of pathogens like the Lyme spirochete Borrelia burgdorferi, but their production is costly and triggers immune responses, leading to complex regulatory systems controlling their gene expression.
- The study identifies the gene bb0268 (flgV) in B. burgdorferi as a structural component of the flagella, rather than the previously thought RNA-binding protein, which plays a significant role in flagellar assembly.
- FlgV is essential for producing functional flagella and affects the bacteria's motility and ability to infect hosts, highlighting its importance in the pathogen's life cycle, especially during infection phases.
Background: Head and neck sarcomas are very rare accounting for about 1% of head and neck malignancies and 5% of sarcomas. Outcomes have historically been worse in this group compared to other sarcomas, due to anatomical constraints that make complete surgical removal difficult and increased local relapse rate. Surgery remains the main intervention although the data suggest the role of chemotherapy and irradiation as treatment options.
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