Publications by authors named "D Soler"
Broaching is a key manufacturing process that directly influences the surface integrity of critical components, impacting their functional performance in sectors such as aeronautics, automotive, and energy. Such components are subjected to severe conditions, including high thermomechanical loads, fatigue, and corrosion. For this reason, the development of predictive models is essential for determining the optimal tool design and machining conditions to ensure proper in-service performance.
View Article and Find Full Text PDFRealization of topological quantum states in carbon nanostructures has recently emerged as a promising platform for hosting highly coherent and controllable quantum dot spin qubits. However, their adjustable manipulation remains elusive. Here, we report the atomically accurate control of the hybridization level of topologically protected quantum edge states emerging from topological interfaces in bottom-up-fabricated π-conjugated polymers.
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- Extra-skeletal osteosarcoma is an uncommon and aggressive type of soft tissue cancer, and this case highlights its rare occurrence in the prostate.
- A 58-year-old man initially diagnosed with prostate adenocarcinoma experienced treatment but had a recurrence of a more aggressive tumor, resulting in additional complications.
- Despite aggressive treatment, including chemotherapy, the disease progressed to metastasize to the lungs and liver, ultimately leading to the patient's death.
Aim: This exploratory study evaluates rating scale usage by experts from the European Reference Network for Rare Neurological Diseases (ERN-RND) for paediatric MD, considering factors like diagnosis, intellectual disability, age, and transition to adult care. The aim is to propose a preliminary framework for consistent application.
Methods: A multicentre survey among 25 ERN-RND experts from 10 European countries examined rating scale usage in paediatric MD, categorizing MD into acute, non-progressive, and neurodegenerative types.
Article Synopsis
- Nine out of 19 genes that code for GABA receptor subunits are linked to disorders associated with seizures and developmental issues.
- The study identified three new de novo missense variants in the GABRA4 gene in patients with epilepsy and various neurodevelopmental problems, highlighting a connection between these genetic changes and neurological symptoms.
- Molecular dynamics simulations showed that the mutated GABRA4 subunits behave differently than the normal ones, supporting the role of this gene in causing a range of neurological conditions.