Publications by authors named "D Soden"

Article Synopsis
  • - The study investigated the link between neurocognitive performance and blood levels of GluA1 autoantibodies in NCAA athletes, comparing contact and noncontact sport participants before and after the season.
  • - Contact sport athletes showed a significant increase in serum GluA1 autoantibodies at the end of the season, regardless of concussion status, while noncontact athletes did not exhibit any changes.
  • - Athletes with higher levels of GluA1 autoantibodies had poorer reaction times, indicating cognitive impairment, which suggests that these autoantibodies could serve as a blood-based marker to identify athletes at risk for cognitive issues, even without a concussion.
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Article Synopsis
  • The study examined how male and female collegiate athletes performed on the SCAT5 concussion assessment and their reported symptoms.
  • Female athletes had better performance scores than male athletes, along with slightly higher symptom reporting.
  • Sex-specific norms improved the ability to identify suspected concussions, suggesting that using these tailored cut points can enhance diagnostic accuracy.
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 Electrochemotherapy is an anticancer treatment that uses electric pulses to facilitate uptake of chemotherapeutic drugs in tumor cells and has proven to have a high local cytotoxic effect with minimal adverse events. Electrochemotherapy has mostly been used in treatment of cutaneous metastases but development of a new endoscopic electrode device has made treatment of colorectal tumors possible. This first-in-man multicenter phase I study investigated safety and efficacy of electrochemotherapy using endoscopic electroporation in patients with colorectal tumors.

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Basal cell carcinoma (BCC) are the commonest cutaneous malignancy and incidence continues to increase. There is a need to expand the therapeutic toolbox to increase options for patients that are unsuitable for or unwilling to undergo the current therapies. Electrochemotherapy (ECT) is a technique where cells are temporarily permeabilized after exposure to a brief pulsed electrical field and combined with low dose chemotherapeutics to ablate malignancies.

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Post-traumatic headache is common after pediatric traumatic brain injury and affects thousands of children every year, but little is known about how headache affects recovery after traumatic brain injury in other symptom domains. We aimed to determine the association between headache and other common symptoms after pediatric traumatic brain injury and explore whether subjective complaints of headache are associated with objective deficits on specialized neurocognitive testing. We conducted a retrospective cohort study of children ages 3-19 years following traumatic brain injury with a completed Sports Concussion Assessment Tool (SCAT) questionnaire.

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