Publications by authors named "D Slama"
Article Synopsis
- This study analyzed the progression of long COVID symptoms over a year, focusing on their effects on daily life and factors influencing symptom relief.
- Out of 231 participants, most experienced ongoing symptoms after 12 months, with a low rate of complete remission and a significant number unable to return to work.
- Key findings suggest that having SARS-CoV-2 antibodies before vaccination can improve recovery chances, while persistent loss of taste (ageusia) decreases the likelihood of improvement.
Objectives: Consequences of COVID-19 on olfactory functions remained unclear during the pandemic. We assessed the efficacy of local budesonide in addition to olfactory rehabilitation when managing non-severe COVID-19 patients with persistent hyposmia.
Methods: A multicentric, randomized, superiority trial was conducted (ClinicalTrials.
Article Synopsis
- The study investigates the immune responses in long COVID patients, focusing on humoral (antibody) and CD4+ T cell responses before vaccination.
- It includes participants who are seropositive and seronegative for antibodies against SARS-CoV-2, comparing them with individuals who recovered from COVID-19 and uninfected controls.
- Results indicate that seronegative long COVID patients have weaker immune responses to the virus, while seropositive patients exhibit strong coordinated antiviral responses, highlighting the complexity of immune reactions in long COVID cases.
Article Synopsis
- Epizootic hemorrhagic disease (EHD) is caused by the EHD virus (EHDV), which has multiple serotypes, with a new strain called EHDV-8 emerging in Tunisia in late 2021.
- The study identified EHDV-8 in deer carcasses in Tunisia during 2021 and 2022 and explored potential insect vectors responsible for its transmission, particularly near Tozeur, where it was confirmed in cattle.
- Genetic analysis revealed that the EHDV-8 sequences from deer and the collected insect vectors were highly similar, indicating close correspondence and confirming the presence of the virus in both species.
Several disabling symptoms potentially related to dysautonomia have been reported in "long-COVID" patients. Unfortunately, these symptoms are often nonspecific, and autonomic nervous system explorations are rarely performed in these patients. This study aimed to evaluate prospectively a cohort of long-COVID patients presenting severe disabling and non-relapsing symptoms of potential dysautonomia and to identify sensitive tests.
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