Publications by authors named "D Skowasch"

Objectives: To longitudinally assesses pulmonary involvement in newly diagnosed rheumatoid arthritis (RA) and psoriatic arthritis (PsA) patients over a 12-months follow-up. To identify biomarkers and establish a diagnostic algorithm for monitoring pulmonary changes.

Methods: Newly diagnosed RA and PsA patients were examined with clinical and laboratory assessments, pulmonary function tests (PFT), and chest radiography (CXR) at three-months intervals for one year.

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Background: Patients with severe asthma (SA) benefit from biologic therapy substantially. However, the impact of smoking-related comorbidities remains unclear due to the exclusion of patients with ≥10 pack-years from asthma studies. Our aim was to examine the effects of emphysema on biologic treatment response in SA in this retrospective cohort study.

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Purpose: Asthma is affecting 4-5% of all adults (10% of children) in Germany, ≥ half are inadequately controlled. In 2019 up to 54 thousand patients suffered from severe uncontrolled asthma, 52% were treated/co-treated by pneumonologists. 45% of them had continuous oral corticosteroid (OCS)- and short-acting β2-agonist (SABA) overuse for ≥2 years.

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Background: The use of online information and communication is globally increasing in the healthcare sector. In addition to known benefits in other medical fields, possible specific potentials of eHealth lie in the monitoring of oncological patients undergoing outpatient therapy. Specifically, the treatment with immune checkpoint inhibitors (ICI) requires intensive monitoring due to various possible negative side effects.

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Article Synopsis
  • - The study investigates the relationship between eosinophils and changes in arteries among asthma patients, given that both conditions are linked to inflammation but previous mediators weren't well understood.
  • - A total of 100 asthma patients were assessed, comparing those with low (< 300/µl) and high (≥ 300/µl) eosinophil blood counts, with findings showing that high eosinophil counts correlated with more severe asthma symptoms and increased arterial stiffness.
  • - Results indicated that higher eosinophil levels were associated with reduced radial strain in the carotid arteries, suggesting potential support for the idea that eosinophils could play a role in the development of atherosclerosis.
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