Publications by authors named "D Skovgaard"
Although estimates of the prevalence of cardiac arrhythmias in healthy volunteers exist, there is a lack of baseline data in other specific populations, such as people living with overweight and obesity, who are increasingly involved in clinical trials. This study investigated the baseline prevalence of arrhythmias in participants with overweight or obesity in 2 phase 1 trials of weight management medications (NCT03661879, NCT03308721). Participants aged 18-55 years, without a history of cardiovascular disease, and with body mass index (BMI) of 25.
View Article and Find Full Text PDFArticle Synopsis
- Tendon injuries can happen to anyone, whether they're active or not, and this study looked at how certain health problems might increase the risk of these injuries.
- The researchers followed 5,856 people for 3 years, finding that around 5.7 out of every 1,000 people developed tendon injuries that needed hospital care.
- They discovered that people with higher blood sugar and cholesterol had a much greater chance of getting tendon injuries, especially in their lower or upper limbs, showing that these health issues make tendons weaker and more likely to get hurt.
Importance: Weight loss improves cardiometabolic risk factors in people with overweight or obesity. Intensive lifestyle intervention and pharmacotherapy are the most effective noninvasive weight loss approaches.
Objective: To compare the effects of once-weekly subcutaneous semaglutide, 2.
In the approval process for new weight management therapies, regulators typically require estimates of effect size. Usually, as with other drug evaluations, the placebo-adjusted treatment effect (i.e.
View Article and Find Full Text PDFAim: To investigate the effects of once-weekly subcutaneous (s.c.) semaglutide 2.
View Article and Find Full Text PDF