In vitro activity of amdinocillin in combination with other beta-lactam antibiotics against aminoglycoside-susceptible and resistant gram-negative bacteria.

Amdinocillin alone and in combination with other beta-lactam antibiotics was tested for in vitro activity against aminoglycoside-susceptible and resistant gram-negative bacteria. Amdinocillin alone or in combination with ampicillin, ticarcillin, piperacillin, cefazolin, cefoxitin, and cefamandole had little to no activity against aminoglycoside-resistant E. coli, E.

Test-of-cure analysis by direct immunofluorescence for Chlamydia trachomatis after antimicrobial therapy.

The direct immunofluorescence assay (DFA) was compared with culture for test-of-cure analysis for Chlamydia trachomatis in patients 7 to 10 days after antimicrobial therapy was given. DFA test-of-cure results correlated with culture results in 79.5% of 39 patients.

Evaluation of a commercial cytotoxicity assay for detection of Clostridium difficile toxin.

A comparative study was performed to determine the accuracy of Clostridium difficile toxin detection. A commercial cytotoxicity assay (Bartels Immunodiagnostic Supply, Bellevue, Wash.) was compared with conventional microcytotoxicity assays, using Vero and MRC-5 cells.

Campylobacter laridis causing bacteremia in an immunosuppressed patient.

An unusual species, Campylobacter laridis , belonging to the group of nalidixic acid resistant thermophilic Campylobacter species, was isolated from the blood of a 71-year-old man with multiple myeloma, hyperviscosity syndrome, and renal failure. The organism was first recognized in the laboratory by gram-stain reaction and resistance to nalidixic acid. The organism differs from C.