Publications by authors named "D Siriwardena"
Article Synopsis
- The study evaluated how well community-based optometrists (CBOs) can assess limbal anterior chamber depth (LACD) for suspected primary angle closure in comparison to consultant ophthalmologists, noting moderate accuracy.
- After implementing an educational intervention, CBOs showed improved agreement and specificity in their assessments, although sensitivity decreased slightly.
- The researchers concluded that a simpler 4-point grading scale would be better for identifying cases and suggested that the educational program could help reduce false positive referrals in real-world settings.
Article Synopsis
- - The study investigates early human trophoblast development using marmoset embryos, bridging gaps in understanding due to the inaccessibility of human early conceptus.
- - Researchers successfully created trophoblast stem cells (TSCs) from marmoset pluripotent stem cells, demonstrating unique characteristics and differentiation potential compared to human TSCs.
- - The findings suggest that specific culture conditions for marmosets can maintain a trophoblast-like identity, revealing insights into evolutionary differences in implantation and enhancing knowledge of human development.
The management of treatment-resistant schizophrenia (TRS) is challenging as the medications involved, often atypical antipsychotics, have a host of associated adverse effects. While complications such as agranulocytosis are well established and necessitate close hematological monitoring, the gastrointestinal effects of particular atypical antipsychotics, such as clozapine, are recognized to a lesser extent. The following case of TRS leading to chronic treatment-resistant pseudo-obstruction, eventually requiring total colectomy, highlights the considerable sequelae of clozapine on the gastrointestinal tract.
View Article and Find Full Text PDFSilicon (Si) is recognized as a promising anode material for next-generation anodes due to its high capacity. However, large volume expansion and active particle pulverization during cycling rapidly deteriorate the battery performance. The relationship between Si anode particle size and particle pulverization, and the structure evolution of Si particles during cycling is not well understood.
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