Publications by authors named "D Sipos"
Glioblastoma, the most common and aggressive primary brain tumor in adults, presents a formidable challenge due to its rapid progression, treatment resistance, and poor survival outcomes. Standard care typically involves maximal safe surgical resection, followed by fractionated external beam radiation therapy and concurrent temozolomide chemotherapy. Despite these interventions, median survival remains approximately 12-15 months, with a five-year survival rate below 10%.
View Article and Find Full Text PDFIntroduction: The COVID-19 pandemic has become a global health crisis, eliciting varying severity in infected individuals. This study aimed to explore the immune profiles between moderate and severe COVID-19 patients experiencing a cytokine storm and their association with mortality. This study highlights the role of PD-1/PD-L1 and the TIGIT/CD226/CD155/CD112 pathways in COVID-19 patients.
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- The study focused on Echovirus type 18 (E18) infections in hospitalized adults with meningoencephalitis during a 2023 epidemic in south-western Hungary.
- Out of 82 cerebrospinal fluid samples tested, 6.1% were positive for enterovirus, with four specifically identified as E18, exhibiting symptoms like headache and fever.
- Genetic analysis revealed that these E18 strains are related to recent, unpublished strains from France and China, indicating the need for ongoing monitoring of E18 variants.
Article Synopsis
- The study looked at burnout among radiologists and radiographers in Hungary because their jobs can be very stressful and demanding.
- Researchers analyzed responses from 406 people, mainly women, and found many had high levels of emotional exhaustion and feelings of not accomplishing enough at work.
- Having pets, especially dogs, and more healthcare experience seemed to help reduce burnout, while working long hours and not having children was linked to higher burnout levels.
Complex Diagnostic Challenges in Glioblastoma: The Role of F-FDOPA PET Imaging.
Pharmaceuticals (Basel)
September 2024
Glioblastoma multiforme (GBM) remains one of the most aggressive and lethal forms of brain cancer, characterized by rapid proliferation and diffuse infiltration into the surrounding brain tissues. Despite advancements in therapeutic approaches, the prognosis for GBM patients is poor, with median survival times rarely exceeding 15 months post-diagnosis. An accurate diagnosis, treatment planning, and monitoring are crucial for improving patient outcomes.
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