Publications by authors named "D Simonyan"
Article Synopsis
- The study investigates the role of 11-oxygenated androgens, particularly 11-ketotestosterone (11KT), in predicting the progression of lethal prostate cancer and the onset of castration-resistant prostate cancer (CRPC).
- Using mass spectrometry on blood samples from 145 patients treated with androgen deprivation therapy, researchers analyzed the relationship between androgen levels and CRPC development.
- Findings suggest higher levels of 11KT are associated with a shorter time to CRPC, indicating that monitoring this hormone could enhance treatment strategies for prostate cancer patients.
Article Synopsis
- Docosahexaenoic acid (DHA), an important omega-3 fatty acid for brain development, was studied to see if high-dose supplementation during the neonatal period could enhance behavioral functioning in very preterm children by age 5.
- In a multicenter randomized controlled trial, 177 children were assessed at 5 years, with 132 completing neurodevelopmental evaluations.
- Results showed no significant improvement in behavioral functioning or secondary outcomes for those who received DHA compared to a placebo, indicating that high-dose DHA did not have the expected positive effects.
Article Synopsis
- This study looks at different types of immune cells in prostate cancer and how they affect the patient's chance of recovery.
- Researchers used lab tests on cancer samples to find out which immune cells are present and how they relate to the severity of the disease.
- They found that certain immune cell types and their amounts could predict if a patient would need more treatment or if the cancer could be deadly.
Background: Cancer is the leading cause of disease-related death among children of more than 1 year of age. However, childhood cancer risk factors and etiology are yet to be fully understood. The goal of this study is to identify geographic variation among children and adolescents diagnosed with pediatric tumors between 2001 and 2018 in the province of Quebec.
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