The Functionalization of Activated Polyester Fabrics with Chitosan-Changes in Zeta Potential and Moisture Management.

In the interests of using green and sustainable chemical innovations to create sustainable products with minimized (or no) chemical hazard potential, the polyester fabric in this work was activated and functionalized with chitosan and its durability was investigated. Chitosan is a natural biopolymer derived from chitin. As it has good biocompatibility, bio-absorption, anti-infectious, antibacterial and hemostatic properties and accelerates wound healing, it is increasingly being researched for the antimicrobial treatment of textiles.

Synthesis and Characterization of Antibacterial Chitosan Films with Ciprofloxacin in Acidic Conditions.

This work presents the results of research on obtaining chitosan (CS) films containing on their surface ciprofloxacin (CIP). A unique structure was obtained that not only gives new properties to the films, but also changes the way of coverage and structure of the surface. The spectroscopic test showed that in the process of application of CIP on the surface of CS film, CIP was converted from its crystalline form to an amorphic one, hence improving its bioavailability.

Ectopically Expressed Meiosis-Specific Cancer Testis Antigen HORMAD1 Promotes Genomic Instability in Squamous Cell Carcinomas.

Genomic instability is a prominent hallmark of cancer, however the mechanisms that drive and sustain this process remain elusive. Research demonstrates that numerous cancers with increased levels of genomic instability ectopically express meiosis-specific genes and undergo meiomitosis, the clash of mitotic and meiotic processes. These meiotic genes may represent novel therapeutic targets for the treatment of cancer.

Evaluation of Polysaccharide-Peptide Conjugates Containing the RGD Motif for Potential Use in Muscle Tissue Regeneration.

New scaffold materials composed of biodegradable components are of great interest in regenerative medicine. These materials should be: stable, nontoxic, and biodegrade slowly and steadily, allowing the stable release of biodegradable and biologically active substances. We analyzed peptide-polysaccharide conjugates derived from peptides containing RGD motif (H-RGDS-OH (), H-GRGDS-NH (), and cyclo(RGDfC) ()) and polysaccharides as scaffolds to select the most appropriate biomaterials for application in regenerative medicine.

Antibacterial and Antifungal Properties of Modified Chitosan Nonwovens.

Chitosan acquires bacteriostatic properties via protonation of its amino groups. However, much of the literature assumes that chitosan itself inhibits the growth of bacteria. This article presents a comparative study of chitosan nonwovens modified with various acids, including acetic, propionic, butyric, and valeric organic acids, as well as hydrochloric acid.