Efficacy of radiosurgery with and without angioembolization: A subgroup analysis of effectiveness in ruptured versus unruptured arteriovenous malformations - An updated systematic review and meta-analysis.

Background: Congenital arterial defects such as cerebral arteriovenous malformations (AVMs) increase brain bleeding risk. Conservative therapy, microsurgical removal, percutaneous embolization, stereotactic radiosurgery (SRS), or a combination may treat this serious disease. This study compares angioembolization with SRS to SRS alone in ruptured or unruptured brain ateriovenous malformations (BAVM) patients.

Dynamic assessment of titanium surface oxides following mechanical damage reveals only partial passivation under inflammatory conditions.

Motivated by clinical problems of titanium implant degradation, we developed a workflow that enabled assessment of surface oxide dynamics as a function of clinical interventions and inflammation conditions. We found that mechanical damage led to decrease of stoichiometric TiO ratio in the passivation oxide film and further resulted in accelerated degradation under inflammatory anaerobic conditions. This method can be employed for the assessment of surface oxides to monitor implant safety.

Development of a Coculture Model for Assessing Competing Host Mammalian Cell and Bacterial Attachment on Zirconia versus Titanium.

Coculture models are limited by bacteria rapidly outcompeting host mammalian cells for nutrients , resulting in mammalian cell death. The goal of this study was to develop a coculture model enabling survival of mammalian cells and oral bacterial species to assess their competition for growth on dental implant materials. Two early colonizing oral bacterial species, or , were grown in coculture with primary human macrophages or human gingival fibroblasts for up to 7 days on tissue-culture treated polystyrene or polished titanium and zirconia disks.

Calcified amorphous tumor attached to the membranous septum: a rare clinical entity.

We report a rare case of a pedunculated calcified amorphous tumor (CAT) of the left ventricle attached by a stalk to the membranous septum in a 74-year-old woman who presented with a cerebrovascular accident. We believe this is the first report of a CAT attached to the membranous septum.