Clinical Presentation of Small Intestinal Bacterial Overgrowth from Aerodigestive Tract Bacteria Versus Colonic-Type Bacteria: A Comparison Study.

Background: Small Intestinal Bacterial Overgrowth (SIBO) is a heterogenous syndrome from excessive bacteria in the small intestine lumen. It is unknown if differences in type of bacterial overgrowth lead to differences in symptoms.

Methods: Patients with suspected SIBO were recruited prospectively.

Impact of colorism and self-rated skin tone in predicting self-esteem among women from Pakistan.

Discrimination is a very complicated, multifaceted, and long lasting problem that prevails in social and even political structure. In subcontinent, the discrimination on the basis of skin color (colorism) is making lives of women miserable who are already victims of various disparities. Colorism was found to be a predictor for both mental and physical health.

Endoscopic Ultrasound-guided Sampling of Solid Pancreatic Lesions: A Comparative Analysis of 25 Gauge 22 Gauge Core Biopsy Needles.

Background: Pancreatic mass sampling has historically been performed by endoscopic ultrasound-guided fine needle aspiration (EUS-FNA). However, its sensitivity has been reported to be within a wide range, which limits its reliability. Fine needle biopsy (FNB) has been shown to have superior diagnostic performance and is increasingly replacing fine needle aspiration.

Failure of the Condyle-C1 Interval Method to Diagnose Atlanto-occipital Dislocation in the Presence of an Associated Atlanto-axial Dislocation: A Case Report.

Atlanto-occipital dislocation (AOD) is a craniocervical injury that has serious neurological consequences and is often fatal. High-speed blunt trauma, such as motor vehicle accidents, that extend and put traction on the head can cause this injury. The current recommendation for diagnosis is to measure the condyle-C1 interval (CCI) using a computed tomography (CT) scan in the coronal plane and more recently in the sagittal plane.

Video Rating in Neurodegenerative Disease Clinical Trials: The Experience of PRION-1.

Background/aims: Large clinical trials including patients with uncommon diseases involve assessors in different geographical locations, resulting in considerable inter-rater variability in assessment scores. As video recordings of examinations, which can be individually rated, may eliminate such variability, we measured the agreement between a single video rater and multiple examining physicians in the context of PRION-1, a clinical trial of the antimalarial drug quinacrine in human prion diseases.

Methods: We analysed a 43-component neurocognitive assessment battery, on 101 patients with Creutzfeldt-Jakob disease, focusing on the correlation and agreement between examining physicians and a single video rater.