Synthesis, characterization, antimicrobial, DNA binding and cleavage studies of mixed ligand Cu(II), Co(II) complexes.

The mixed ligand complexes MLA of Cu(II) and Co(II) with Schiff base derived from 4-amino antipyrine and 5-NO(2) salicylaldehyde (2,3 -dimethyl-1-phenyl-4-(2-hydroxy-5-nitro benzylideneamino)-pyrazol-5-one) as ONO donor (L) and A = 2,2 bipyridine (bpy),1,10 phenonthroline (1,10 phen) as N, N donor ligands have been prepared, owing to their biological and other applications. The structural features have arrived from their elemental analyses, magnetic susceptibility, molar conductance, Mass, IR, UV-VIS, powdered XRD and ESR spectral studies, that established MLA type of composition for the metal complexes. The electronic absorption spectral data of the complexes suggest an octahedral geometry around the central metal ion.

Synthesis, characterization, antibacterial, DNA binding and cleavage studies of mixed ligand Cu(II), Co(II) complexes.

Mixed-ligand Cu(II), Co(II) complexes of formulae [Co(NSALT)(A.A)(H2O)](1), [Co(OHAPT)(A.A)H2O](2), and [Cu(ESALT)(ABPH)H2O] (3) were obtained by refluxing methanol solutions of copper, cobalt chlorides with the appropriate ligands.