Particulates in CGT guidance survey results - an ISCT process development & manufacturing committee perspective on cell and gene therapy industry knowledge awareness.

The International Society for Cell & Gene Therapy Particulates Working Group has surveyed the global industry on commonly used regulatory guidance documents pertaining to particulates across various cell and gene therapy (CGT) product-based chemistry and manufacturing controls. Responses were collated from academic and industrially based individuals involved in or making decisions for manufacturing, quality control and analytics. Two surveys covering therapy developers and manufacturing suppliers were created and distributed via e-mail, through focus groups and via social media platforms.

Immediate Effect of on Heart Rate Variability in Patients with Hypertension: A Randomised Controlled Study.

Background: Hypertension, a prevalent cardiovascular condition, is linked to autonomic nervous system dysregulation, often evidenced by reduced heart rate variability (HRV). Yoga, particularly , may influence autonomic control and improve HRV, thus offering potential benefits for hypertension management.

Purpose: This study intended to assess the impact of the regular use of practice on HRV among hypertensive patients.

Exploring Bleomycin vs. Setrol Injections in Adults.

This retrospective study aimed to assess the efficacy of bleomycin and sodium tetradecyl sulphate (STS) as sclerotherapeutic treatment modalities for low-flow vascular and lymphatic malformations. A total of 30 patients in age group of 9-60 years with vascular and lymphatic anomalies in the head and neck region were included in our study and divided into two groups of 15 each. Patients in group 1 received bleomycin injections, while group 2 received STS for treatment.

SAGA: Stability-Aware Gait Analysis in constraint-free environments.

Background: Gait abnormality detection is a challenging task in clinical practice. The majority of the current frameworks for gait abnormality detection involve the individual processes of segmentation, feature estimation, feature learning, and similarity assessment. Since each component of these modules is fixed and they are mutually independent, their performance under difficult circumstances is not ideal.