Publications by authors named "D Serraino"
Introduction: The relations between coffee and tea consumption and head and neck cancer (HNC) incidence are unclear. With increasing global HNC burden, this study aims to examine the association between coffee, tea, and HNC.
Methods: A pooled analysis of 9548 HNC cases and 15,783 controls from 14 individual-level case-control studies was conducted from the International Head and Neck Cancer Epidemiology consortium.
The aim of this study is to investigate the prognostic role of body mass index (BMI) on survival from head and neck cancer (HNC). We performed a pooled analysis of studies included in the International Head and Neck Cancer Epidemiology consortium. We used Cox proportional hazards models to estimate the adjusted hazard ratios (HR) for overall survival and HNC-specific survival, and we stratified the results according to cancer site.
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- Head and Neck Squamous Cell Cancer (HNSCC) is a significant health concern, ranking sixth among global cancers, with a pressing need for new therapies and biomarkers due to slow advancements in treatment personalization.!* -
- This study analyzed the somatic mutations in 15 specific genes related to HNSCC in a high-incidence area of Italy, finding unique mutation patterns that may have prognostic implications, particularly in the hypopharyngeal region.!* -
- The research revealed that while certain mutations indicate poorer prognosis, they currently lack sufficient evidence to be used as predictive biomarkers, highlighting the necessity for further studies to improve treatment options for HNSCC patients.!*
Article Synopsis
- The study evaluates cancer incidence trends from 2008-2017 in Italy among individuals aged 20-49, utilizing data from 20 cancer registries that cover about one-third of the population.
- Results show that cancer rates were nearly double for women compared to men, particularly due to breast and thyroid cancers, with significant variations in incidence trends across different cancer types.
- The findings indicate no consistent increase for early-onset cancers in Italy, with rising rates for some cancers offset by declines in others, underscoring the need for preventive measures and careful screening strategies.
Article Synopsis
- Five-year survival rates for vulvar squamous cell carcinoma (VSCC) patients in Italy haven't improved over the past 30 years, which raises concerns about treatment effectiveness.
- A study of cancer registries found that in 2018, about 6,620 women in Italy were living with VSCC, but only 32% of newly diagnosed patients are considered curable, with many facing high mortality rates even after five years.
- The results highlight a critical need to revamp the vulvar care approach in Italy to better address the ongoing challenges in managing VSCC.