Publications by authors named "D Serfaty"

Novel male contraceptives have been in development for well over half a century, and despite a robust predicted global market for new methods, funding for research and development has been extremely limited. While the pharmaceutical industry previously supported male contraceptive research and development, industry partners are only spectators in the current space, awaiting a product that has been de-risked by the public sector before re-entering the field. Current male contraceptive development efforts are thus primarily funded by nonprofit, non-governmental, and government agencies who also act as the primary advocates for the field.

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Background: While several studies have noted smell impairment in schizophrenia, it is unclear whether this impairment extends to acute psychosis and whether it is associated with more severe illness as expressed in extended hospitalization.

Objectives: To evaluate the olfactory function of patients in an acute psychotic state and correlate it with clinical symptomatology and length of hospitalization.

Methods: Olfactory function was assessed in 20 patients with schizophrenia in their first week of hospital admission for acute psychosis compared with matched controls.

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Article Synopsis
  • - This study (BZK40+) investigated the effectiveness and safety of a spermicide containing benzalkonium chloride in women aged 40 and above, aiming to assess its contraceptive efficacy over 12 months.
  • - A total of 151 women participated, with a high retention rate; 95.4% completed the initial 6-month phase, and 41.7% opted to continue for another 6 months, applying the spermicide in 96.3% of their sexual encounters.
  • - Remarkably, the study reported a Pearl Index of 0 pregnancies during the 12-month period, indicating effective contraception, but the authors suggest caution in interpreting these results due to the usual lower efficacy of spermicides
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