Publications by authors named "D Senthamarai Kannan"
The pathogenic mechanisms of many diseases are well understood at the molecular level, but there are prevalent syndromes associated with pathogenic signaling, such as diabetes and chronic inflammation, where our understanding is more limited. Here, we report that pathogenic signaling suppresses the mobility of a spectrum of proteins that play essential roles in cellular functions known to be dysregulated in these chronic diseases. The reduced protein mobility, which we call proteolethargy, was linked to cysteine residues in the affected proteins and signaling-related increases in excess reactive oxygen species.
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- - The text discusses the importance of learning outcomes in education and how integrating "A-SMART" (Action-oriented, Specific, Measurable, Achievable, Relevant, Time-bound) outcomes with the backward design process can enhance curriculum planning.
- - It introduces a three-stage approach for educators: define desired results, determine acceptable evidence of learning, and plan learning activities, highlighting the significance of starting with action verbs.
- - By adopting this method, educators can create clearer, more effective learning outcomes that improve assessment practices and educational experiences while addressing potential challenges in the process.
Article Synopsis
- Pelvic organ prolapse (POP) is prevalent among women over 50, with sacrocolpopexy being a common surgical treatment, though it can lead to complications like bowel dysfunction and urinary incontinence.
- This study compares the outcomes of robotic sacrocolpopexy and ileopectopexy, analyzing data from 35 patients who underwent these procedures between 2021 and 2023.
- Results indicated that ileopectopexy had no complications compared to sacrocolpopexy, which had some bowel issues, suggesting that ileopectopexy could be a safer alternative, although further research is necessary to confirm these results.
Introduction: This study evaluates the safety and feasibility of the Medtronic Hugo robot-assisted surgery (RAS) system in gynecological and urogynecological procedures. Through a retrospective analysis of prospectively collected data from the first 100 surgeries performed at Apollo Hospitals Chennai, we aim to provide insights into the system's effectiveness, including outcomes, complications, and overall surgical efficiency in major gynecological and urogynecological operations.
Methods: A single experienced robotic surgeon conducted the surgeries, including hysterectomies (n=66).
the parasite responsible for nearly all cases of severe malaria, must survive challenging environments to persist in its human host. Symptomatic malaria is characterized by periodic fevers corresponding to the 48-hour asexual reproduction of in red blood cells. As a result, has evolved a diverse collection of heat shock proteins to mitigate the stresses induced by temperature shifts.
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