Publications by authors named "D Scribano"

Background: Acinetobacter baumannii poses a significant threat globally, causing infections primarily in healthcare settings, with high mortality rates. Its adaptability to antibiotic resistance and tolerance to various stresses, including reactive oxygen species (ROS), contribute to its persistence in healthcare environments. Previous evidence suggested that the periplasmic heat shock protein, HslJ-like protein (ABUW_2868), could be involved in oxidative stress defense in A.

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Background: Anisakis spp. are zoonotic nematodes causing mild to severe acute and chronic gastrointestinal infections. Chronic anisakiasis can lead to erosive mucosal ulcers, granulomas and inflammation, potential tumorigenic triggers.

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Microbiota plays a crucial role in intestinal maturation in preterm newborns. The clinical manifestation of the immaturity of the gastro-intestinal tract is called feeding intolerance (FI). This condition may resolve spontaneously or dramatically evolve into necrotizing enterocolitis.

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Article Synopsis
  • Carbapenemase-producing bacteria, particularly KPC-3-producing sequence type (ST) 512, pose a significant global health threat, with increasing resistance to advanced treatments like ceftazidime/avibactam (CZA).
  • This study analyzed three isolates from a single patient over 78 days, including two that originated from a liver abscess, focusing on their antimicrobial resistance and genetic characteristics.
  • The final isolate, hmv-318Kp, demonstrated CZA resistance and a hypermucoviscous phenotype due to specific genetic mutations, indicating an evolution of this strain in terms of infectivity and resistance mechanisms.
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