Publications by authors named "D Scott Painter"
Lower risk (LR) myelodysplastic syndromes (MDS) are heterogeneous hematopoietic stem and progenitor disorders caused by the accumulation of somatic mutations in various genes including epigenetic regulators that may produce convergent DNA methylation patterns driving specific gene expression profiles. The integration of genomic, epigenomic, and transcriptomic profiling has the potential to spotlight distinct LR-MDS categories on the basis of pathophysiological mechanisms. We performed a comprehensive study of somatic mutations and DNA methylation in a large and clinically well-annotated cohort of treatment-naive patients with LR-MDS at diagnosis from the EUMDS registry (ClinicalTrials.
View Article and Find Full Text PDFMore and more nursing homes are admitting residents receiving dialysis. In 2023, the Centers for Medicare and Medicare Services released guidance addressing the qualifications of those caring for these residents and further clarified the survey process. The American Nephrology Nurses Association Board of Directors created the Home Dialysis for Nursing Home Residents Task Force to review the revised guidance, investigate strategies and opportunities for nephrology registered nurses in home dialysis therapy in this setting, and consider the potential implications related to alternative home dialysis settings.
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- The study investigates the occurrence, causes, treatment, and recovery times of ulnar collateral ligament (UCL) injuries in NFL quarterbacks between 1991 and 2023.
- A total of 21 injuries were recorded, with most occurring in players aged around 29, primarily as noncontact injuries, and often managed without surgery.
- While average recovery time was about 166 days, those requiring surgical reconstruction faced significantly longer recovery; additionally, recent injuries correlated with better performance after recovery compared to older injuries.
Article Synopsis
- Softball is a widely played sport with high injury rates, particularly among females, making it a popular focus for injury research.
- The study analyzed injury data from the National Electronic Injury Surveillance System between 2012 and 2021, revealing that 68.1% of upper extremity injuries were in female athletes, with significant age differences between genders.
- Injury rates decreased overall during the decade, with fielding activities and player-ball contact being the most common causes of injuries among varied age groups.
Article Synopsis
- Brain injuries can lead to hidden disabilities that are often hard to detect, and traditional assessment methods for these impacts are not very precise, resulting in unreliable treatment estimates.
- The research introduced 'The Attention Atlas', an immersive virtual reality game developed to better assess unilateral spatial neglect in brain injury patients, categorizing individuals into three groups based on their gameplay: neglect, minor atypicality, or non-neglect.
- Findings from the study indicated that VR assessments identified neglect in 25.5% of patients, which is higher than the 17.6% identified through standard assessments, showcasing the potential of VR technology in improving diagnostic accuracy.