Postoperative epidural analgesia with bupivacaine and fentanyl: hourly pain assessment in 348 paediatric cases.

Background: The objective of this prospective study was the evaluation of the analgesia provided by an epidural infusion of bupivacaine and fentanyl after different types of surgery in children.

Methods: Data were collected from 348 epidural analgesia in 87 children below 2 years of age, in 80 children between 2 and 6 years and 181 above 6 years of age, for a median duration of 43 postoperative hours. Bupivacaine (mean concentration 0.

Fentanyl versus sufentanil: plasma concentrations during continuous epidural postoperative infusion in children.

No pharmacokinetic data are available with respect to the plasma concentrations and fentanyl or sufentanil during epidural administration in children. This double-blind randomized study included 12 children (5-12 yr). Patients in group F were given an epidural loading dose of fentanyl 1.

[Bone infections due to Aeromonas hydrophila--apropos of 2 case reports].

The authors report on two cases of bone infection due to Aeromonas hydrophila: one case in a compound fracture and the other a late infection in an implant. They confirm the rapid onset of systemic infectious disease but not the magnitude of local manifestations. The use of modern antibiotics sensitive to Aeromonas proved effective in lowering the risk of dramatic local evolution which has been described.

[Passage of propofol in the colostrum. Preliminary data].

So as to ascertain whether propofol passed into human milk, a study was carried out in five women who had undergone general anaesthesia with propofol in the puerperium. Concentrations of propofol were measured both in plasma and colostrum. The results showed clearly the excretion of propofol in the colostrum, and the similar time-courses of propofol levels in the blood and colostrum; the ratio of concentrations blood:colostrum was close to 1.