Publications by authors named "D Schwartz"
Background: Cancer researchers frequently consider the use of single-arm and randomized controlled clinical trial designs that leverage external data. The literature has reported extensively on how the use of external data can introduce bias through a variety of distortion mechanisms. In this article, we focus on a distortion mechanism that is often overlooked: informative censoring.
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- IPF development involves a two-hit process: an initial vulnerability of the lung's epithelial cells followed by a second injury that triggers fibrotic changes.
- Genetic factors play a crucial role in the first hit, while ongoing damage disrupts normal cell function and activates fibroblasts, leading to lung fibrosis.
- Understanding IPF in terms of its stages may lead to new treatments that target these underlying causes, aiming for a shift from palliative care to potential cures for patients.
Objective: To examine how rural residence interacts with SES and race/ethnicity relative to Head and neck squamous cell carcinoma (HNSCC) treatment delay and outcomes.
Methods: The SEER database was queried for patients aged ≥18 with HNSCC. Out of 164,337 cases, 126,052 remained after exclusions for missing data.