Publications by authors named "D Schocken"
Background: In nondiabetic people, the long-term effects of insulin resistance (IR) on heart failure (HF) and all-cause mortality have not been studied.
Objectives: To examine the association between IR trajectories and incident HF and all-cause mortality in a nondiabetic population.
Methods: We studied 7835 nondiabetic participants from the Atherosclerosis Risk in Communities (ARIC) Study.
Background: Fasting glucose (FG) demonstrates dynamic fluctuations over time and is associated with cardiovascular outcomes, yet current research is limited by small sample sizes and relies solely on baseline glycemic levels. Our research aims to investigate the longitudinal association between FG and silent myocardial infarction (SMI) and also delves into the nuanced aspect of dose response in a large pooled dataset of four cohort studies.
Methods: We analyzed data from 24,732 individuals from four prospective cohort studies who were free of myocardial infarction history at baseline.
Article Synopsis
- The diagnosis of left ventricular hypertrophy (LVH) through ECG primarily relies on measuring the QRS voltage, but this method often lacks sensitivity.
- A new approach emphasizes the understanding of electrical properties of the heart muscle and factors influencing QRS voltage beyond just size, including both spatial and non-spatial determinants.
- This perspective reveals a wide variety of QRS patterns in LVH patients, indicating that a normal QRS complex can still exist despite underlying complications, and highlights the importance of interpreting these changes for assessing cardiovascular risk.
Heart failure (HF) prevention is an urgent public health need with national and global implications. Stage A HF patients do not show HF symptoms or structural heart disease but are at risk of HF development. There are no unique recommendations on detecting Stage A patients.
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- The diagnosis of Left Ventricular Hypertrophy (LVH) using ECG mainly relies on measuring the increased amplitude of the QRS complex in specific leads.
- The traditional understanding suggests that a larger left ventricular mass produces a stronger electrical field, leading to heightened QRS forces and amplitudes.
- However, studies show that only a small percentage of LVH patients actually exhibit this increased QRS amplitude, indicating that the current voltage criteria have low sensitivity, prompting a discussion on potential reasons and the introduction of a new diagnostic approach.