Role of Lugol solution before total thyroidectomy for Graves' disease: randomized clinical trial.

Background: Lugol solution is often administered to patients with Graves' disease before surgery. The aim is to reduce thyroid vascularization and surgical morbidity, but its real effectiveness remains controversial. The present study was designed to evaluate the effects of preoperative Lugol solution on thyroid vascularization and surgical morbidity in patients with Graves' disease undergoing total thyroidectomy.

Total adrenalectomy versus subtotal adrenalectomy for bilateral pheochromocytoma: meta-analysis.

Background: Bilateral pheochromocytomas are rare and often heritable. Total adrenalectomy leads to a definitive oncological cure, with subsequent definitive hypocortisolism. Subtotal adrenalectomy is a possible alternative.

Lactam-fused tropolones: a new tunable, environmentally sensitive fluorophore class.

Fluorescent small-molecules capable of altering their profiles in response to environmental changes are exceptionally valuable tool compounds throughout the scientific community. The following manuscriipt describes a new class of fluorescent small molecules based on lactam-fused tropolones that are responsive to a dynamic range of environmental changes. These molecules can be easily obtained through a rapid annulation procedure between appropriately functionalized tropolones and primary amines, which is often complete within minutes at room temperature.

New Potential Biological Limiters of the Main Esca-Associated Fungi in Grapevine.

The strains TH07.1-NC (TH), MX95 (AA), AL142PE (PE) and ALPO (PO) were tested as biological limiters against Fme22.12 (FM), Pm22.

Long-Term Outcomes after Surgery for Pheochromocytoma and Sympathetic Paraganglioma.

Background: The prognosis of pheochromocytoma and sympathetic paraganglioma (PHEO/sPGL) is difficult to predict at the time of diagnosis and long-term follow-up data are scarce, especially for apparently benign and sporadic variants. The aim of the study was to analyze the long-term outcomes in PHEO/sPGL patients.

Methods: A monocentric series of 170 patients who underwent surgery for PHEO/sPGL was analyzed.