Publications by authors named "D Savant"
Introduction: Indeterminate oncocytic/Hürthle cell lesions on thyroid cytology are reflexed to molecular testing. This study aims to examine the cytologic characteristics of thyroid fine-needle aspiration (FNA) smears with oncocytes classified as atypia of undetermined significance (AUS) with particular molecular patterns that can aid in determining a more conclusive Bethesda category upfront thus decreasing unnecessary testing and associated costs.
Materials And Methods: Our pathology database was searched for thyroid FNAs with AUS for oncocyte predominance from 2019 to 2022.
Introduction: Solid pseudopapillary neoplasm (SPN) is a tumor of young females with gain-of-function mutation in catenin beta 1 gene involved in Wnt signal transduction pathway. Beta-catenin immunohistochemistry (IHC) is used to diagnose SPN. Lymphoid enhancer-binding factor 1 (LEF-1) has been recognized in the transactivation of Wnt pathway.
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- - The study focuses on the role of fine needle aspiration (FNA) in assessing salivary gland tumors, specifically looking into the “Salivary Gland Neoplasm of Uncertain Malignant Potential” (SUMP) category as defined by the Milan System.
- - Researchers analyzed FNA cases from three academic institutions to determine the risk of neoplasm (RON) and risk of malignancy (ROM) in different SUMP subtypes, finding that overall ROM for SUMP was 20.8%, with clear cell subtype having a high malignancy rate.
- - Results showed variability in ROM across institutions and SUMP subtypes, reinforcing the necessity for precise categorization of SUMP lesions, particularly clear cell types, for effective
Objectives: To investigate the relationship between food insecurity and developmental delay and/or behavior problems (DD/PB) in US children aged 2 to 5 years before the COVID-19 pandemic.
Methods: Data from 14,464 children aged 2 to 5 years from the National Survey of Children's Health from 2016 to 2017 were analyzed. Children with food insecurity came from families reporting they sometimes or often could not afford nutritious meals.
Cryptogenic multifocal ulcerating stenosing enteropathy is a rare idiopathic small bowel enteropathy characterized by multiple small intestinal strictures and superficial ulcerations, often with clubbing. We present a case of a 25-year-old man who originally initially presented with small bowel obstruction believed to be secondary to suspected Crohn's disease who was ultimately diagnosed with cryptogenic multifocal ulcerating stenosing enteropathy.
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