[Electrophysiological analysis of functional state of spinal cord motoneurons in rats with parathyroprivous tetany].

In normal rats and of those with parathyroprivous (hypocalcemic) tetany the comparative analysis of background activity (BA), tetanic and posttetanic increase and decrease of frequency of spinal cord (SC) motoneurons (MNs) responses under high-frequency (50, 100Hz) stimulation (HFS) of flexor (G) and extensor (P) hind-limb nerves have been conducted. The on-line selection and program analysis of the spikes was produced. On the 3-7 and 21-22 days of development of acute and chronic tetany, respectively, the significant tetanic and posttetanic changes of MNs activity without meaningful changes in BA was registered.

[Electrophysiological and morphohistochemical study of adrenalectomy on the hippocampal neurons].

Chronic insufficiency of adrenal hormones is a pathology leading to brain dysfunction. In electrophysiological studies, by extracellular recording of spike activity of single hippocampal neurons (HN) caused by high-frequency stimulation of the entorhinal cortex (EC) in rats with unilateral removal of adrenal (adrenalectomy - AE), we analyzed mechanisms of adaptation of neural networks to chronic hormonal deprivation. The balance of excitatory and inhibitory responses, recorded in HN of intact rats was submitted to characteristic changes in dynamics of development of neurodegeneration: the dominating in norm inhibitory responses were decreased at all AE terms (from 42 % to 25 % by the 18th week).

[Can the thalamic projections of medulla oblongata nucleus Z be reorganized following partial deafferentation of the ventral lateral thalamic nucleus?].

Following partial deafferentation of ventral lateral thalamic nucleus by means of HRP retrograde labeling, possible plastic reorganization of projections of the brain stem relay Z nucleus was studied in cats. The partial deafferentation of ventral lateral thalamic nucleus was evoked by preliminary (3 months before) destroying of contralateral cerebellar nucleus interpositus or Deiters' lateral vestibular nucleus. The local intensive labeling of neurons in the Z nucleus and a little group of neurons in the cellular group x of the vestibular complex projecting to ventral lateral thalamic nucleus and overlapping with those projecting from cerebellum was observed.

[Protective effect of Vipera raddei venom damage of peripheral nerve].

In rats, single pulse activity of inter- and motoneurons of the spinal cord lumbar segment was studied in stimulation of cut. n. ischiadicus, extensor (n.