This study aims to use diffusion tensor imaging (DTI) in conjunction with brain graph techniques to define brain structural connectivity and investigate its association with personal income (PI) in individuals of various ages and intelligence quotients (IQ). MRI examinations were performed on 55 male subjects (mean age: 40.1 ± 9.
View Article and Find Full Text PDFMultiple Sclerosis (MS) is an autoimmune disease that combines chronic inflammatory and neurodegenerative processes underlying different clinical forms of evolution, such as relapsing-remitting, secondary progressive, or primary progressive MS. This identification is usually performed by clinical evaluation at the diagnosis or during the course of the disease for the secondary progressive phase. In parallel, magnetic resonance imaging (MRI) analysis is a mandatory diagnostic complement.
View Article and Find Full Text PDFConvolutional Neural Networks (CNNs) with U-shaped architectures have dominated medical image segmentation, which is crucial for various clinical purposes. However, the inherent locality of convolution makes CNNs fail to fully exploit global context, essential for better recognition of some structures, e.g.
View Article and Find Full Text PDFAutomated segmentation of new multiple sclerosis (MS) lesions in 3D MRI data is an essential prerequisite for monitoring and quantifying MS progression. Manual delineation of such lesions is time-consuming and expensive, especially because raters need to deal with 3D images and several modalities. In this paper, we propose Pre-U-Net, a 3D encoder-decoder architecture with pre-activation residual blocks, for the segmentation and detection of new MS lesions.
View Article and Find Full Text PDFThe main goal of this study is to investigate the discrimination power of Grey Matter (GM) thickness connectome data between Multiple Sclerosis (MS) clinical profiles using statistical and Machine Learning (ML) methods. A dataset composed of 90 MS patients acquired at the MS clinic of Lyon Neurological Hospital was used for the analysis. Four MS profiles were considered, corresponding to Clinical Isolated Syndrome (CIS), Relapsing-Remitting MS (RRMS), Secondary Progressive MS (SPMS), and Primary Progressive MS (PPMS).
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