Publications by authors named "D Sanchez-Rodriguez"
[ESPEN guideline on clinical nutrition and hydration in geriatrics].
Geriatr Psychol Neuropsychiatr Vieil
September 2024
Article Synopsis
- Advanced chronic kidney disease affects muscle health, making it important to find effective ways to assess muscle quality before kidney transplants.
- Musculoskeletal ultrasound, particularly measuring rectus femoris (RF) echogenicity, shows promise in identifying muscle weakness and quality issues in patients waiting for kidney transplants.
- In a study of 112 patients, a RF echogenicity cut-off of 70 demonstrated good sensitivity but moderate specificity for detecting quadriceps weakness, indicating an increased risk in patients with greater echogenicity.
Background/objectives: Despite the effectiveness of exercise and nutritional interventions to improve aerobic capacity and quality of life in lung transplant (LT) recipients, their compliance is low. Strategies to reduce the high attrition rate (participants lost over time) is a major challenge. Artificial neural networks (ANN) may assist in the early identification of patients with high risk of attrition.
View Article and Find Full Text PDFThe MADS-box gene XAANTAL1 participates in Arabidopsis thaliana primary root growth and columella stem cell patterns in response to ROS, via direct regulation of PEROXIDASE 28 and RETINOBLASTOMA-RELATED genes.
J Exp Bot
January 2025
Article Synopsis
- The balance between cell growth and differentiation in plants is influenced by gene regulatory networks and signal transduction pathways, particularly involving reactive oxygen species (ROS) and transcription factors (TFs).
- In the model organism Arabidopsis thaliana, the MADS-box transcription factor XAANTAL1 (XAL1) plays a crucial role in mediating the effects of hydrogen peroxide (H2O2) on primary root growth and stem cell identity.
- XAL1 enhances H2O2 levels in the root meristem by regulating stress response genes and is key to inhibiting primary root growth through its negative regulation of peroxidase and catalase activities, while also promoting columella stem cell differentiation.
Resistance exercise and protein supplementation are recognized as effective treatment strategies for age-related sarcopenia; however, there are limited data on their feasibility, tolerability, and safety. The primary outcome of this study was feasibility, evaluated through the 15-item TELOS (Technological, Economics, Legal, Operational, and Scheduling) feasibility components and by recruitment, retention, and consent rates. Tolerability was measured by examining permanent treatment discontinuation, treatment interruption, exercise dose modification, early termination, rescheduling of missed sessions, losses to follow-up, attendance, and nutritional compliance.
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