Publications by authors named "D Salvatori"
Human pluripotent stem cells (hPSCs) tend to acquire genetic aberrations upon culture in vitro. Common aberrations are mutations in the tumor suppressor TP53, suspected to confer a growth-advantage to the mutant cells. However, their full impact in the development of malignant features and safety of hPSCs for downstream applications is yet to be elucidated.
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- The study developed functional beverages using jarilla, a medicinal plant from Argentina, and blueberry juice sweetened with lemon honey, utilizing maltodextrin for encapsulation.
- Both beverages exhibited high water solubility and retained significant polyphenol and flavonoid contents after spray-drying, while anthocyanins were less stable.
- The powdered version showed strong antioxidant properties and potential inhibition of key digestive enzymes, with favorable sensory evaluations, indicating its viability as a non-toxic functional food.
Article Synopsis
- The development of human induced pluripotent stem cell (iPSC)-based therapies is hindered by the absence of specific markers to identify differentiated cell types, particularly notochordal-like cells and chondrocytes, which are essential for treating back pain and osteoarthritis.
- Researchers created two iPSC lines featuring an ACAN-2A-mScarlet reporter to help isolate and study these important cells, bypassing the need for specific markers.
- The versatility of ACAN as a marker for various tissues emphasizes its potential for enhancing research in developmental biology and regenerative medicine.
Introduction: In veterinary education programs it is important to have a balance between providing students with valuable hands-on experience and ensuring the ethical treatment and welfare of the animals involved. In the last years simulation-based veterinary education played an important role helping with the replacement of experimental animals in education and at the same time creating a safe learning environment offering endless options for training in a safe environment. The aim of this systematic review was to discern which type of learning outcomes are used to evaluate specific learning goals of clinical skills training and to grasp the impact of diverse simulator characteristics on the measured learning outcomes in clinical skills training.
View Article and Find Full Text PDFHip dysplasia causes major disability in dogs. Treatment options are limited to palliative treatment (e.g.
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