Publications by authors named "D Salvan"
Article Synopsis
- The management of upper aerodigestive tract cancers is intricate, prompting the creation of a reference framework to define optimal treatment principles, led by a multidisciplinary scientific committee.
- A systematic literature review was conducted to develop evidence-based recommendations that account for various patient-specific factors and treatment quality criteria.
- The comprehensive framework aims to standardize care, enhance decision-making in consultations, and ensure equitable treatment practices, with plans for future updates to maintain relevance.
Article Synopsis
- Head and neck cancer significantly affects the quality of life (QoL) of older patients, with this study evaluating the impact of geriatric-assessment (GA)-based interventions on QoL over two years.
- The study involved 475 patients aged 65 and older, comparing those who received a GA-driven intervention to those receiving standard care, using specific QoL questionnaires for measurement.
- Results showed improvements in QoL scores overall, but no major differences between the intervention and control groups; most patients in the intervention group did not complete the full treatment, highlighting the need for better healthcare models tailored to patients' needs.
This study assesses the efficacy of Geriatric Assessment (GA)-driven interventions and follow-up on six-month mortality, functional, and nutritional status in older patients with head and neck cancer (HNC). HNC patients aged 65 years or over were included between November 2013 and September 2018 by 15 Ear, Nose, and Throat (ENT) and maxillofacial surgery departments at 13 centers in France. The study was of an open-label, multicenter, randomized, controlled, and parallel-group design, with independent outcome assessments.
View Article and Find Full Text PDFSomatic mutational landscape of extracranial arteriovenous malformations and phenotypic correlations.
J Eur Acad Dermatol Venereol
June 2022
Background: Somatic genetic variants may be the cause of extracranial arteriovenous malformations, but few studies have explored these genetic anomalies, and no genotype-phenotype correlations have been identified.
Objectives: The aim of the study was to characterize the somatic genetic landscape of extracranial arteriovenous malformations and correlate these findings with the phenotypic characteristics of these lesions.
Methods: This study included twenty-three patients with extracranial arteriovenous malformations that were confirmed clinically and treated by surgical resection, and for whom frozen tissue samples were available.