Publications by authors named "D Salmon"
Background: Alzheimer's disease neuropathologic change (ADNC) and Lewy pathology (LP) often coexist in cognitively impaired individuals. These pathologies' relative distribution and severity may modify these individuals' clinical presentation, cognitive profile, and prognosis. Therefore, we examined the contributions of LP and concomitant ADNC to disease survival and profiles of cognitive decline in preclinical and clinical stages in a large neuropathologically diagnosed group.
View Article and Find Full Text PDFPurpose: Neurological symptoms often prominent in post-acute sequelae of COVID-19 (PASC) necessitate deeper understanding. Our objective was to investigate brain metabolism in PASC and examine correlations with neurological symptoms during both the acute and chronic stages.
Methods: Eighty-seven adults experiencing PASC with neurocognitive symptoms were recruited in the PERSICOR prospective study and examined using brain [18F]FDG PET/CT.
Article Synopsis
- This study investigated eye and small blood vessel issues in patients who experienced symptoms after recovering from COVID-19, analyzing 44 patients mostly around 47 years old.
- Using advanced imaging techniques, researchers found significant retinal abnormalities, including hyperreflective dots and areas of capillary non-perfusion, indicating compromised blood flow.
- The results suggest that these retinal changes are linked to reduced capillary density, highlighting the importance of microvascular damage instead of just lasting problems with a protective layer around blood vessels.
While COVID-19 vaccines are generally very safe, the risks of myocarditis and pericarditis has been established following mRNA vaccines, with the highest risk in young males. Most systematic reviews and meta-analyses of the risk of myocarditis or pericarditis have included passive surveillance data, which is subject to reporting errors. Accurate measures of age-, sex-, vaccine dose-, and vaccine type-specific risks are crucial for assessment of the benefits and risks of the vaccination.
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